buy Opana ER 5 mg Pain Killer online

(1 customer review)


Opana ER 5 mg is a narcotic analgesics class drug, it can be Identified as a Blue Color pill that is Round in shape. “E612 5” is written on one side of the tablet and is plain with no imprint on another side.

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Opana ER 5 mg is an extended-release Pain Killer Tablet. It helps in relieving severe ongoing pain. it is a long-acting pain medication.

Side Effects Opana ER 5 mg:

Common Side effects of this medicine are Chest pain, Slow Heart rate, Fever, Headache, vomiting, indigestion, and sedation. Some side effects are not common in most people but need not worry about, including Euphoric mood, Temporary breathing suspension, and Agitation. For some people, this medicine can cause serious side effects may occur. These side effects may include Mood changes, Vision changes, and abdominal pain.

How Long Does Opana ER 5 mg Last in the body?

This is a slow-releasing Drug. It starts working in 60-90 minutes. The effects of this medicine can be felt for 11-12 hours.


Dosage Forms & Strengths

tablet, immediate-release: Schedule II

  • 5mg
  • 10mg

tablet, extended-release: Schedule II

  • 5mg
  • 7.5mg
  • 10mg
  • 15mg
  • 20mg
  • 30mg
  • 40mg

reformulated extended-release tablet (Opana ER)

  • Opana ER was discontinued from the market at the request of the FDA owing to a significant shift in the route of abuse from nasal to injection following the product’s reformulation Injection abuse of reformulated.
  • Opana ER has been associated with a severe outbreak of HIV, hepatitis C, and thrombotic microangiopathy.

Moderate-to-Severe Pain

Acute pain

  • Immediate-release tablets are indicated for acute moderate-to-severe pain where the pain is severe enough to require an opioid analgesic and for which alternative therapies are inadequate.
  • Opioid-naive patients (immediate-release): 10-20 mg PO q4-6 hr PRN initially, then titrated as warranted (may start with Opana ER 5 mg increments)

Chronic Severe Pain

Extended-release oxymorphone is indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate.

Extended-release tablet initial dosing

  • Patients who are opioid-naive or not opioid-tolerant
    • Opana ER 5 mg PO q12hr initially, then titrated in increments of 5-10 mg q12hr every 3-7 days to level that provides adequate analgesia and minimizes side effects
  • Opioid-tolerant patients
    • Opioid-tolerant definition: Patients who are receiving, for 1 week or longer, at least 60 mg/day PO morphine, 25 mcg/hr transdermal fentanyl, 30 mg/day PO oxycodone, 8 mg/day PO hydromorphone, 25 mg/day PO oxymorphone, or an equianalgesic dose of another opioid
    • Conversion from immediate-release to extended-release oxymorphone: Administer one-half of total immediate-release daily dose as extended-release q12hr
    • Conversion from other opioids: Refer to equianalgesic recommendations within the prescribing information

Dosage Modifications

Renal impairment

  • Immediate-release tablet; CrCl <50 mL/min: Initiate therapy at lowest dose (eg, 5 mg); titrate to effect slowly; monitor
  • Extended-release tablet
    • CrCl <50 mL/min (opioid-naïve): Initiate with 5 mg PO q12hr
    • CrCl <50 mL/min (prior opioid therapy): Initiate at 50% lower than the starting dose for a patient with normal hepatic function and titrate slowly

Hepatic impairment Opana ER 5 mg

  • Mild; immediate-release or injection: Initiate therapy at lowest dose; titrate to effect slowly; monitor
  • Moderate to severe: Contraindicated
  • Extended-release
    • Mild (opioid-naïve): Initiate with 5 mg PO q12hr
    • Mild (prior opioid therapy): Initiate at 50% lower than the starting dose for a patient with normal hepatic function and titrate slowly
    • Moderate or severe: Contraindicated

Dosing Considerations

Immediate-release tablets

  • Limitations of use Opana ER 5 mg
    • Because of the risks of addiction, abuse, and misuse of opioids, even at recommended doses, reserve use when alternative treatment options (e.g., nonopioid analgesics, opioid/opioid antagonist combination products) have not been tolerated or are not expected to be tolerated, or have not provided adequate analgesia, or are not expected to provide adequate analgesia.

Extended-release tablets

  • Limitations of use Opana ER 5 mg
    • Because of the risks of addiction, abuse, and misuse with opioids, even at recommended doses, and because of the more significant chances of overdose and death with extended-release formulations, reserve for use in patients for whom alternative treatment options (e.g., non-opioid analgesics or immediate-release opioids) are ineffective, not tolerated, or would be otherwise inadequate to provide sufficient pain management.
    • Extended-release formulations are not indicated as an as-needed (PRN) analgesic.

Access to naloxone for opioid overdose

  • Assess the need for naloxone upon initiating and renewing treatment
  • Consider prescribing naloxone
    • Based on the patient’s risk factors for overdose (e.g., concomitant use of CNS depressants, a history of an opioid use disorder, prior opioid overdose); the presence of risk factors should not prevent proper pain management
    • Household members (including children) or other close contacts are at risk for accidental ingestion or overdose
  • Consult patients and caregivers on the following:
    • Availability of naloxone for emergency treatment of opioid overdose
    • Ways differ on how to obtain naloxone as permitted by individual state dispensing and prescribing requirements or guidelines (e.g., by prescription, directly from a pharmacist, as part of a community-based program)

Additional information


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1 review for buy Opana ER 5 mg Pain Killer online

  1. Jerry Frizt

    I have a genetic predisposition for neck arthritis and my genes did their job. Grrr! After over THIRTY YEARS of level 10+ pain in my neck and that radiated to my shoulders and back, I’m having to figure out how to describe NOT being in pain! Yay!

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